{"product_id":"bpc-157-tb500-20mg","title":"BPC 157\/TB500 20mg","description":"\u003cp\u003eBPC-157 + TB500 is a peptide research blend consisting of two extensively studied investigational peptides: BPC-157 (Body Protection Compound-157) and TB500 (a synthetic peptide fragment derived from Thymosin Beta-4).\u003c\/p\u003e\n\u003cp\u003eBPC-157 is a synthetic pentadecapeptide composed of 15 amino acids and modeled after a peptide sequence associated with proteins found in gastric tissue. TB500 is a laboratory-produced peptide derived from the naturally occurring Thymosin Beta-4 protein, which is involved in cellular migration, cytoskeletal organization, and tissue-response pathways.\u003c\/p\u003e\n\u003cp\u003eResearchers have investigated these peptides individually and in combination for their potential interactions with biological processes involved in cellular signaling, tissue remodeling, vascular response, angiogenesis-related pathways, connective tissue biology, and inflammatory signaling mechanisms.\u003c\/p\u003e\n\u003cp\u003eScientific interest in this peptide combination stems from the complementary biological pathways associated with each peptide in preclinical and experimental research settings.\u003c\/p\u003e\n\u003ch3\u003eMechanism Overview\u003c\/h3\u003e\n\u003cp\u003eBPC-157 has been investigated for potential interactions with:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eNitric oxide signaling pathways\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eVEGF-related angiogenesis\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eEndothelial function\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eFibroblast activity\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eExtracellular matrix remodeling\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCellular signaling involved in tissue-response mechanisms\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTB500 has been investigated for potential interactions with:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eActin regulation and cytoskeletal organization\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCellular migration pathways\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTissue remodeling processes\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAngiogenesis-related mechanisms\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCellular differentiation pathways\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eInflammatory signaling pathways\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese mechanisms remain investigational and are primarily based on preclinical and laboratory research.\u003c\/p\u003e\n\u003ch3\u003eStructure\u003c\/h3\u003e\n\u003ch4\u003eBPC-157\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eSequence: GEPPPGKPADDAGLV\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCAS: 1375250-19-6\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eMolecular Weight: ~1419.5 g\/mol\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eTB500 (Thymosin Beta-4 Fragment)\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eSequence: LKKTETQ\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCAS: Varies by manufacturer and peptide fragment specification\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSynthetic peptide fragment derived from Thymosin Beta-4\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eQuality\u003c\/h3\u003e\n\u003cp\u003eQuality testing is an integral part of evaluating peptides, as purity alone does not provide a complete picture of product quality.\u003c\/p\u003e\n\u003cp\u003eA comprehensive quality review should include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eHPLC purity testing to assess related impurities\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eLC-MS or LC-MS\/MS testing to confirm molecular identity\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePeptide content (assay) testing to verify labeled quantity\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eResidual solvent analysis when applicable\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eEndotoxin screening and contaminant testing\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEach batch is supported by a lot-specific Certificate of Analysis (COA) detailing test methods, results, testing dates, and laboratory information.\u003c\/p\u003e\n\u003ch3\u003eEvidence Status\u003c\/h3\u003e\n\u003cp\u003eCurrent evidence for both BPC-157 and TB500 is primarily preclinical. Neither peptide has an FDA-approved therapeutic indication.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eSikiric, P., et al. (2020). Stable gastric pentadecapeptide BPC 157, Robert's stomach cytoprotection, and adaptive cytoprotection. Current Pharmaceutical Design, 26(24), 2671–2695.\u003c\/p\u003e\n\u003cp\u003eSeiwerth, S., et al. (2014). BPC 157 and blood vessels. Current Pharmaceutical Design, 20(7), 1121–1125.\u003c\/p\u003e\n\u003cp\u003eHe, L., et al. (2022). Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157 in rats and dogs. Frontiers in Pharmacology, 13, 1026182.\u003c\/p\u003e\n\u003cp\u003eChang, C. H., et al. (2011). The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology, 110(3), 774–780.\u003c\/p\u003e\n\u003cp\u003eGoldstein, A. L., \u0026amp; Kleinman, H. K. (2015). Advances in the basic and clinical applications of thymosin beta 4. Expert Opinion on Biological Therapy, 15(S1), S139-S145.\u003c\/p\u003e\n\u003cp\u003eMalinda, K. M., et al. (1999). Thymosin beta 4 accelerates wound healing. Journal of Investigative Dermatology, 113(3), 364–368.\u003c\/p\u003e\n\u003ch3\u003eResearch Use Only\u003c\/h3\u003e\n\u003cp\u003eAll products on this site are intended for research and development use only.\u003c\/p\u003e\n\u003cp\u003eProducts are not for human consumption of any kind. The statements made on this website have not been evaluated by the U.S. Food and Drug Administration. The products offered by this company are not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003cp\u003eAll products are sold strictly for research, laboratory, analytical, or educational purposes only and are not intended for human consumption, veterinary use, or clinical application.\u003c\/p\u003e","brand":"Wholesale Site ","offers":[{"title":"10","offer_id":66826116923437,"sku":null,"price":1.0,"currency_code":"USD","in_stock":true},{"title":"20","offer_id":66826116956205,"sku":null,"price":1.0,"currency_code":"USD","in_stock":true},{"title":"30","offer_id":66826116988973,"sku":null,"price":1.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0756\/9086\/8781\/files\/ChatGPT_Image_Jun_2_2026_07_46_09_AM_1.png?v=1780406250","url":"https:\/\/theawell.bio\/products\/bpc-157-tb500-20mg","provider":"TheaWell Bio","version":"1.0","type":"link"}